make a big difference

基本解释

That information can make a big difference in the campaigns and offers made to members of such a household.
由此获得的讯息可以极大地区分这样一个家庭中成员的活动和出价的不同。
When you make a big difference with just a few minutes – or dollars – you’ll always remember how important and amazing you are.
当你花费一些时间或者一些钱，结果却会是很大的不同。你会一直记得你自己是多么重要和了不起。
First of all, the members of the Trash-Site Safety Council are not listed, which could make a big difference in the believability of the study.
其一，垃圾场安全委员会的成员没有被清楚列举出来，这一点可令该研究的可信度产生巨大的差异。

A few degrees can make a big difference when it comes to food storage.
But whether or not you do so doesn't seem to make a big difference.
但不论你是否选择这样做,都不会有什么太大的影响
耶鲁公开课 - 心理学导论课程节选
Primarily the people who started are Emerson and Moscovici and many others who have done research showing how minority-- very often one person can make a big difference, can make a significant difference.
爱默生和莫斯科维奇是先驱,他们和其他学者都证明少数人-,经常是一个人，如何实现重大改变，能实现显著的改变。
哈佛公开课 - 幸福课课程节选

But if you are designing a collaborative session, it can make a big difference.
FORBES: Want Collaboration? Watch Where You Sit.