wrinkle up

基本解释

A smile comes very easy — you can wrinkle up with cheer.
来一个微笑很容易──嘴角欢快翘起来，你能百次微笑，可难得挤出一滴泪；
So once cigarettes wrinkle up your face, you'll have a harder time correcting the damage with cosmetic surgery than people who've never smoked.
所以一旦吸烟使你产生皱纹，通过整形手术修复损害，你将比不吸烟的人更痛苦。
ScienceDaily (May 25, 2011) — A new biomaterial designed for repairing damaged human tissue doesn't wrinkle up when it is stretched.
每日科学（2011年5月25日）---一种拟用于人体损伤组织修复的新生物材料在拉伸时并没有产生褶皱。

So for older folks with high medical expenses and relatively low incomes, the long-term care premium tax deduction is more likely to come into play than for middle-aged folks. (Another wrinkle: under ObamaCare, starting Jan. 1, 2013, the 7.5% floor goes up to 10% unless the taxpayer or his or her spouse is 65 or older).
FORBES: Uncle Sam Can Help You Pay For Long-Term Care Insurance